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Bringing Cutting-Edge Research to the Forefront

Cutting-edge research and innovative insight await you at the 2017 Freston conference. This is your opportunity to engage the foremost investigators in GI and extracellular vesicles (EVs) and delve deeper into vesicle biogenesis and secretion — revealing its relevance to GI diseases and clinical applications.

Explore Novel Research

Gain insight on the latest basic and translational research to better understand the role of EVs in disease pathogenesis.

Engage in Scientific Dialogue

Speak with experienced and up-and-coming researchers about the diagnostic and therapeutic potential of EVs.

Foster Collaboration

Connect with more than 100 researchers from multiple therapeutic areas to expand your network.

Influence Future Research

Discuss the evolving progress of EV research and help identify critical areas where further study is needed.


Register early to receive a significant discount and reserve your spot at the conference. Online registration ends Friday, Aug. 25, 2017. After this date, only on-site registrations will be permitted. Registrations made on site are subject to the availability of space.


June 15 – Aug. 25
$430/AGA Members
  • Nonmembers: $530
  • AGA Member Trainee/Student: $130
Register Now

On Site

Sept. 9 – Sept. 10
$530/AGA Members
  • Nonmembers: $630
  • AGA Member Trainee/Student: $180
Register Now

Not an AGA member?

Submit a completed membership application with your course registration and pay the AGA member rate.

*If applying for AGA membership, your application must be received no later than June 7, 2017, to qualify for the AGA member early rate.

**If applying for AGA membership, your application must be received no later than Aug. 14, 2017, to qualify for the AGA member standard rate.

Cancellation Policy

A refund (minus a $50 processing fee) will be given for cancellations received in writing on or before Friday, Aug. 25, 2017. Please send requests to AGA Member Relations via email (, fax (301-272-1774) or mail (4930 Del Ray Avenue, Bethesda, MD 20814).

No cancellations will be accepted for refunds after Aug. 25, 2017. Refunds cannot be made for no shows.

Key Questions Examined

How are extracellular vesicles released from apical and basolateral membrane domains of epithelial cells?

What role do extracellular vesicles play in obesity and cell migration?
How are extracellular vesicles helping in the diagnosis of cancer?
What extracellular-based therapies are currently being developed in GI disorders?


Saturday, Sept. 9

7-8 a.m. Registration and Continental Breakfast
8–8:15 a.m. Welcome and Opening Remarks
Nicholas F. LaRusso, MD, AGAF
Session 1 — Discovery: Biogenesis and Secretion

Moderators: Nicholas F. LaRusso, MD, AGAF, and Harmeet Malhi, MBBS

8:15–9 a.m. Keynote Address: EV in GI Tumorigenesis
David Lyden, MD, PhD
9–9:30 a.m. Biogenesis, Secretion and Characterization of EV Population
Clotilde Thery, PhD
9:30–10 a.m. Protein Sorting into EV
Stephen Gould, PhD
10–10:30 a.m. Coffee Break
Session 2 — Discovery: Biogenesis and Secretion (Cont'd)

Moderators: Clotilde Thery, PhD, and Alissa Weaver, PhD

10:30–11 a.m. Cargo Sorting by KRAS into EV
Robert J. Coffey, MD
11–11:30 a.m. Lipids in EV Biogenesis
Harmeet Malhi, MBBS
11:30 a.m.–noon Domain-Specific Secretion of Exosomes from Polar Epithelia
Nicholas F. LaRusso, MD, AGAF
Interactive Lunch
Noon–1:15 p.m.
Session 3 — Translation: Disease Relevance

Moderators: Robert J. Coffey, MD, and Gregory Gores, MD

1:15–1:45 p.m. Mechanisms of EV Released by Stressed Hepatocytes
Gregory Gores, MD
1:45–2:15 p.m. Immune Regulation by EV in Liver Disease Models
Gyongyi Szabo, MD, PhD
2:15–2:45 p.m. Bacteria-Derived Microvesicles in the Gut-Brain Axis
John Bienenstock, MD, FRCP
2:45–3:15 p.m. Coffee Break
Session 4 — Translation: Disease Relevance (Cont'd)

Moderators: David Lyden, MD, PhD, and Gyongyi Szabo, MD, PhD

3:15–3:45 p.m. EV in Obesity
Robert J. Freishtat, MD, MPH
3:45–4:15 p.m. EV Regulation of Directional Cell Migration
Alissa Weaver, MD, PhD
4:15–5 p.m. Young Investigator Talk
Interactive Poster Session
5–6:30 p.m.

Sunday, Sept. 10

Session 5 — Application: Diagnosis and Therapeutics

Moderators: Ariel E. Feldstein, MD, and John Bienenstock, MD, FRCP

8–8:30 a.m. EV miRNA: Liquid Biopsies for Disease Diagnosis
Tushar Patel, MBChB
8:30–9 a.m. EV in Epithelial Integrity and Wound Repair in the Gut
Asma Nusrat, MD
9–9:30 a.m. Diagnostic Utility of EV in Pancreatic Cancer
Raghu Kalluri, MD, PhD
9:30–10 a.m. Coffee Break
Session 6 — Application: Diagnosis and Therapeutics (Cont'd)

Moderators: Tushar Patel, MD, NMChB, and Asma Nusrat, MD

10–10:30 a.m. EV-Based Therapy in GI Disease
Huang-Ge Zhang, MD, PhD
10:30–11:15 a.m. Young Investigator Talk
11:15–11:45 a.m. TBD
Jim G. Patton, PhD
11:45 a.m.–12:15 p.m. Circulating EV-Based Molecular Diagnostic
Ariel E. Feldstein, MD
12:15–12:25 p.m. Closing Remarks
Nicholas F. LaRusso, MD, AGAF
Robert J. Coffey, MD
12:30–1:15 p.m.

Save up to $50 if you register by June 14.


Nicholas F. LaRusso, MD, AGAF

Nicholas F. LaRusso, MD, AGAF

Conference Co-Chair

Mayo Clinic
Robert J. Coffey, MD

Robert J. Coffey, MD

Conference Co-Chair

Vanderbilt University Medical Center

John Bienenstock, MD, FRCP
McMaster Brain-Body Institute at St. Joseph’s Healthcare Hamilton

Ariel E. Feldstein, MD
University of California, San Diego
Rady Children’s Hospital, San Diego
University of South Carolina

Robert J. Freishtat, MD, MPH
Children’s National Medical Center

Gregory J. Gores, MD
Mayo Clinic

Stephen Gould, PhD
Johns Hopkins Medicine

Raghu Kalluri, MD, PhD
MD Anderson Cancer Center

David Lyden, MD, PhD
Weill Cornell Medicine

Harmeet Malhi, MBBS
Mayo Clinic

Asma Nusrat, MD
University of Michigan

Tushar Patel, MBChB
Mayo Clinic

James G. Patton, PhD
Vanderbilt University

Gyongyi Szabo, MD, PhD
University of Massachusetts Medical School

Clotilde Thery, PhD
Institute Curie, INSERM U932

Alissa Weaver, MD, PhD
Vanderbilt University

Huang-Ge Zhang, MD, PhD
University of Louisville

Share Your Research

Students, trainees and junior faculty are encouraged to submit an abstract for a chance to share their extracellular vesicle research as a poster or oral presentation. Only a select number of abstracts will be chosen for oral presentation. Abstracts must be submitted no later than Thursday, June 15, 2017 at 5 p.m. ET.


InterContinental St. Paul Riverfront

Located at 11 East Kellogg Blvd., St. Paul, MN 55101, room blocks have been reserved for attendees of the AGA James W. Freston Conference.

Room Rate

$155 single/double per night, plus applicable taxes.


You may make your hotel reservation by calling 1-866-686-2867. Be sure to mention you are attending the 2017 AGA James W. Freston Conference to receive the discounted rate. Reservations must be guaranteed with a major credit card equal to one night’s room and tax.


Rooms must be reserved by Friday, Aug. 18 to ensure availability and the discounted rate.


Cancellations must be made 72 hours prior to arrival in order to avoid charges for the first night’s room and tax. Reservations may only be cancelled by calling the hotel directly at 1-800-424-6835, or 651-605-0197, and obtaining a cancellation number. No-shows will be charged first night’s room and tax.

Intercontinental St. Paul Riverfront

InterContinental St. Paul Riverfront

Contact Us

For questions related to the program, contact Jamie Parreco, director of council operations.

For questions related to registration and AGA membership, contact AGA Member Relations at 301-654-2055 or by email.

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4930 Del Ray Ave.
Bethesda, MD 20814

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